United States. Goldenseal (Hydrastis canadensis) Root, Cut and Sifted, Certified Organic.
Goldenseal, a member of the Buttercup family that grows as a perennial in Southeastern Canada and the Eastern US, was a revered Native American and Eclectic remedy, used to soothe inflammatory conditions affecting the mucous membranes of the respiratory, digestive, and genitourinary systems.
Much of its effects appear to be related to the presence of isoquinoline alkaloids, mainly hydrastine, berberine, berberastine, canadine, candaline, and hydrastinine. Its bitter components stimulate secretions of the liver, gall bladder, and spleen, and revive the appetite. Berberine in particular has been extensively studied for its anti-microbial, immune-boosting, and astringent actions.
Goldenseal should not be used during pregnancy.
Cech, NB, Junio, HA, Ackermann, LW, Kavanaugh, JS, Horswill, AR. (2012). Quorum Quenching and Antimicrobial Activity of Goldenseal (Hydrastis canadensis) against Methicillin-Resistant Staphylococcus aureus (MRSA). Planta Medica, 78(14), 1556–1561.
Cecil CE, Davis JM, Cech NB, Laster SM. (2011). Inhibition of H1N1 influenza A virus growth and induction of inflammatory mediators by the isoquinoline alkaloid berberine and extracts of goldenseal (Hydrastis canadensis). Int Immunopharmacol. Nov;11(11):1706-14.
Yamaura, K, Shimada, M, Nakayama, N, & Ueno, . (2011). Protective effects of goldenseal (Hydrastis canadensis L.) on acetaminophen-induced hepatotoxicity through inhibition of CYP2E1 in rats. Pharmacognosy Research, 3(4), 250–255.
*These statements have not been evaluated by the FDA. These products are not intended to diagnose, treat, cure or prevent any disease. As with any herb, consulting a doctor before you begin taking Goldenseal is recommended.